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KMID : 0812020080140010032
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Korean Journal of Neurogastroenterology and Motility
2008 Volume.14 No. 1 p.32 ~ p.38
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Gastroesophageal and Gastropharyngeal Reflux in Patients with Globus and Hoarseness
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Park Chan-Won
Kim Kyung-Yup
Kim Gwang-Ha
Kang Dae-Hwan
Song Geun-Am
Lee Sun-Mi
Choi Cheol-Woong
Park Chan-Ho
Park Hyoung-Yoel
Eum Jae-Sup
Ha Tae-In
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Abstract
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Background/Aims: Globus pharyngeus and hoarseness are common extraesophageal manifestations in the patients with gastroesophageal reflux disease. The aim of this study was to evaluate the frequency of gastroesophageal and gastropharyngeal reflux in the patients with globus and/or hoarseness.
Methods: From July 2004 to December 2006, we retrospectively analyzed the medical records and the findings from endoscopy, esophageal manometry and ambulatory 24-hour pH monitoring of patients with symptoms of globus pharyngeus or hoarseness.
Results: One hundred fifty patients (51.7%, 150/290) complained typical reflux symptoms such as heartburn or acid regurgitation. Two hundred thirty-six patients underwent endoscopy. Reflux esophagitis and hiatal hernia were found in 12.2% (29/236) cases and 5.9% (14/236) cases, respectively. Abnormal esophageal motilities were found on 64.8% of patients showed abnormal esophageal motilitiy tests. Ineffective esophageal motility was the most frequent finding. Two hundred sixty-six patients underwent ambulatory 24-hour dual probe pH monitoring. Of them, normal PH monitoring , GERD only , GPRD only and both GERD and GPRD were 34.2% (91/266), 14.3% (38/266), 15.0% (40/266) and 36.5% (97/266), respectively.
Conclusions: In a high proportion of the patients with globus pharygeus and hoarseness, gastroesophageal reflux disease and gastropharyngeal reflux disease were observed. (Kor J Neurogastroenterol Motil 2008;14:32-38)
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KEYWORD
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Globus, Hoarseness, Gastroesophagealreflux, Gastropharyngealreflux
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